Drugs metabolized by acetylation
SHIP
- Sulfonamides including dapsone
- Hydralazine
- Isoniazid (INH)
- Procainamide
Acetylator polymorphism:Some individuals are slow acetylators and some are fast acetylators.The drugs metabolized by acetylation may become ineffective in fast acetylators and cause toxicity in slow acetylators.
