Hemoglobin and myoglobin: binding strengths, sites
Mnemonic for Hemoglobin and myoglobin: binding strengths, sites
"ABC" of glycosylated Hb (Hb1c):
· Glucose binds to Amino terminal of Beta Chain.
"HbF binds Forcefully":
· HbF binds oxygen more forcefully than HbA, so Oxy-Hb dissociation curve shifts to left.
Stored blood is SOS:
· Stored blood Hb binds to Oxygen Strongly because of decrease in 2,3 BPG.
2,3 BPG binding site is BBC:
· BPG binds to Beta Chain of Hb.
Myoglobin binding strength is MOM:
· Myoglobin binds Oxygen More strongly than Hb.
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